Glucosamine production from poultry for osteoarthritis

06:00 | 07/02/2021 Science - Technology

(VEN) - Vietnam has begun producing supplements rich in glucosamine and chondroitin sulphate (CS) derived from poultry processing for its high proportion of osteoarthritis sufferers. The project is also contributing to stable poultry production and raising farmers’ incomes. 

glucosamine production from poultry for osteoarthritis
Products of the research topic

The production is part of a biotechnology development and application project in the processing industry managed by the Ministry of Industry and Trade (MoIT) and assigned to the NOVA Biotechnology and Pharmaceutical Chemistry Institute.

Project manager, Dr. Dang Tran Hoang explained that CS and glucosamine are active ingredients that support the formation of bone connective tissue and reduce calcium loss, commonly used to treat osteoarthritis, inflammation, breakdown and eventual loss of cartilage.

According to the Transparency Market Research (TMR) Company, as the global population ages, the CS market is forecast to reach US$457.7 million by the end of 2025, compared with US$343.9 million in 2016.

Some 35 percent of Vietnam’s population is estimated to be suffering from osteoarthritis, especially affecting their knees. The World Health Organization (WHO) has ranked Vietnam among the countries with the highest rates of osteoarthritis in the world. According to estimates of the Ministry of Health, Vietnam spends millions of US dollars on imported drugs to treat osteoarthritis, including many products containing CS and glucosamine.

Reducing imports

“No company in Vietnam has ever produced CS and glucosamine. Some enterprises have imported these preparations for capsule production. Currently, only a few products rich in glucosamine and CS for osteoarthritis patients are produced in Vietnam,” Dr. Dang Tran Hoang confirmed.

He said byproducts of poultry processing containing CS and glucosamine include the feet, trachea, breast and cartilage of chickens and ducks. While, shark fin cartilage or crocodile trachea contained only 18 percent of CS, chicken breast cartilage contains 30 percent. In addition, the CS content in duck trachea is 3.6 percent, while in chicken feet cartilage the CS content is about 2.5 percent and 13 percent glucosamine.

Chicken feet cartilage is readily available in domestic chicken processing facilities and imported chickens. It is estimated that a poultry processing facility can supply two tonnes of chicken feet cartilage a day, which is currently only used for animal feed. “Therefore, the topic has high scientific and practical significance and the two preparations have great application prospects to make high value supplements, beneficial to public health, and reduce foreign imports of similar products,” Dr. Dang Tran Hoang emphasized.

Vietnam plans to build technological process models to produce glucosamine and CS preparations from poultry by-products with a volume of 150-200 kilograms per batch, yielding 300,000 glucosamine and CS-rich capsules.

Tam An